Wireless small-scale medical robots have the unique capability of navigating, operating and staying inside hard-to-reach, tight, risky and deep sites inside our body. This talk reports our recent milli- and microscale wireless miniature medical robots down to cell size that could achieve various minimally invasive medical functions, such as targeted active drug delivery, neural stimulation, clot opening, liquid biopsy, biofluid pumping, cauterization, and hyperthermia. Due to miniaturization limitations on on-board actuation, powering, sensing, computing and communication, new materials and methods need to be introduced in creating and controlling such robots. Moreover, they need to be tracked under medical imaging modalities, such as ultrasound, fluoroscopy, photoacoustic imaging, and MRI, for their precise and safe operation. 3D microprinting and assembly-based fabrication methods and biocompatible and multifunctional soft composites with embedded micro/nanomaterials are proposed to create novel medical milli/microrobots. Soft-bodied medical miniature robot designs enable active shape programming-based adaptive, multimodal and multifunctional navigation and functions, and safe operation. External physical forces, such as magnetic fields, acoustic waves and light, and physical or chemical (e.g., catalytic) interactions with the operation medium are used to actuate and steer such miniature robots wirelessly as a single robot or robot collectives. These robots are aimed to save lives of more patients by curing diseases not possible or hard to cure and decrease the side effects and invasiveness of disease treatments drastically. 無線小型醫療機器人擁有獨特的導航、操作能力，并能駐留在人體內難以觸及、狹窄、危險和深處的部位。本次報告將介紹我們近期研發的毫米級至微米級（小至細胞尺寸）無線微型醫療機器人，它們能夠實現多種微創醫療功能，例如靶向主動給藥、神經刺激、血栓清除、液體活檢、生物流體泵送、燒灼和高溫治療。 由于在機載驅動、供能、傳感、計算和通信方面存在微型化限制，需要引入新材料和新方法來創建和控制此類機器人。此外，為了確保其操作的精確性和安全性，需要在超聲、熒光透視、光聲成像和磁共振成像（MRI）等醫學成像模態下對它們進行跟蹤定位。 我們提出采用三維微打印和基于組裝的制造方法，以及嵌入微/納米材料的生物相容性多功能軟復合材料，來制造新型醫療毫米/微米機器人。軟體醫療微型機器人設計能夠實現基于主動形狀編程的自適應、多模式和多功能的導航與操作，并確保安全運行。 利用外部物理力（如磁場、聲波和光）以及與操作介質發生的物理或化學（例如催化）相互作用，可以無線驅動和引導此類微型機器人，無論是單個機器人還是機器人集群。這些機器人旨在通過治療目前無法或難以治愈的疾病來挽救更多患者的生命，并大幅降低疾病治療的副作用和侵入性。

Nature has evolved highly sophisticated machinery for organic synthesis, many of which resemble molecular assembly-line processes. So far chemists have been able to apply this type of approach in the synthesis of peptides, oligonucleotides and polysaccharides but it is much more difficult to apply iterative methodologies to organic synthesis.Here, we describe the application of iterative homologation of boronic esters using chiral lithiated carbamates and chloromethyllithium enabling us to grow carbon chains with control over both relative and absolute stereochemistry. Application of this strategy to the synthesis of the proposed structure of baulamycin and the real structure will be presented as well as other complex targets. 自然界已進化出高度精密的有機合成機制，其中許多類似分子裝配流水線過程。迄今為止，化學家已能將這類方法應用于肽、寡核苷酸和多糖的合成，但將迭代方法應用于有機合成仍困難得多。我們在此闡述如何通過手性鋰化氨基甲酸酯和氯甲基鋰實現硼酸酯的迭代同系化反應，從而能夠可控地構建碳鏈——包括相對與絕對立體化學的精準調控。該策略不僅將應用于bauromycin抗生素原定結構與真實結構的全合成驗證，還將展示其在其他復雜目標分子合成中的應用。

生物制造作為生物技術與先進制造深度融合的顛覆性范式，已成為全球新一輪科技革命和產業變革的制高點。其通過重構物質生產底層邏輯，推動制造業向綠色化、智能化、可持續化躍遷，是培育新質生產力、重塑全球競爭格局的核心引擎。生物制造作為生物技術產業的重要組成部分，是生物基產品實現產業化的基礎平臺，也是合成生物學等基礎科學創新在具體過程中的應用。未來生物制造相關技術將滲透到包括能源、材料、醫藥、食品、環境保護等多個行業的發展，對我國的傳統產業的轉型升級也將起到極為重要的作用。目前全球生物制造產業正處于技術攻堅和商業化應用開拓的關鍵階段，發展先進生物制造技術，對于促進我國經濟與環境協調與可持續發展、積極應對經濟全球化與國際競爭，具有重大戰略意義。本報告對全球生物制造產業發展現狀、戰略需求進行分析，圍繞現階段存在的問題，對未來生物制造發展的重點方向提出相關建議。

模空間，旨在參數化幾何對象，在代數幾何中具有核心地位。Mumford對負曲率曲線模空間的構造，構成了現代模空間理論發展的一個關鍵里程碑。對于高維代數簇，負曲率情形的模理論由Kollár等人系統發展，并與極小模型綱領形成了深刻關聯。相比之下，正曲率情形，亦即Fano簇的模空間構造，則長期以來面臨重大挑戰，是高維幾何中一個懸而未決的問題。近年來的重大進展表明，問題的核心在于對K-穩定性的深入理解。K-穩定性最初由田剛院士在復幾何背景下提出，后經Donaldson的代數化重述，用以刻畫K?hler-Einstein度量的存在性。本報告旨在梳理相關理論的發展脈絡，闡釋代數幾何與復幾何之間的相互作用，并重點討論K-穩定性在Fano簇模空間構造中所發揮的核心作用。

Photovoltaic cells using molecular dyes, semiconductor quantum dots or perovskite pigments as light harvesters have emerged as credible contenders to conventional devices. Dye sensitized solar cells use a three-dimensional nanostructured junction for photovoltaic electricity production. They possess unique practical advantages in particular highly effective electricity production from ambient light, ease of manufacturing, flexibility and transparency, bifacial light harvesting, and aesthetic appeal, which have enabled industrial mass production and commercial applications. They served as a launch pad for perovskite solar cells which are presently being intensively investigated as one of the most promising future PV technologies, the power conversion efficiency of solution processed laboratory cells having currently reached 27 %. Present research focusses on ascertaining their long-term operational stability and scale up to pilot production of large modules. My lecture will cover our most recent findings in these revolutionary photovoltaic domains. 采用分子染料、半導體量子點或鈣鈦礦色素作為光捕獲材料的光伏電池，已成為傳統器件的強勁競爭者。染料敏化太陽能電池通過三維納米結構結實現光電轉換，具備獨特的實用優勢：包括弱光環境高效發電、易于制造、柔性與透明度俱佳、雙面采光能力以及美學吸引力，這些特質促成了其工業化量產與商業應用。該技術更為鈣鈦礦太陽能電池的發展奠定基礎——后者作為最具前景的未來光伏技術之一，其溶液加工實驗室電池的功率轉換效率目前已達27%，現階段的重點研究在于確認其長期運行穩定性，并推進大型組件的試點量產。本次演講將涵蓋我們在這些革命性光伏領域的最新研究成果。

我們介紹費馬提出的無窮下降法，探討其在數論經典問題中的應用。無窮下降法通過構造矛盾性“無窮遞減序列”，以反證形式否定解的存在性或揭示數的本質性質。費馬運用這個方法給出了整數1不是同余數的證明；給出了佩爾方程解的遞推結構。另外的例子還包括指數四的費馬大定理和兩平方和問題。